GasGasGas - Anaesthetic Science for Anaesthesia!

More vivacast action (a busy season) Ollie tackles pharmacology questions spanning isomerism, Local anaesthetics and anticholinergic agents Listen to find out more! ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted upon. This information is not a suitable substitute for medical advice. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. Where…

We tumble into a flatspin at 35000 ft, the landing gear is of no use, so you reach for vasopressin instead of the ejector seat. But how can it remediate this situation, should you look for DDAVP instead? Or was it a Terlispin! Have I seen TopGun recently, is this a seriously intriguing episode on vasopressin and its mates that will put your brain into a nose dive? All possible, you will have to listen and decide for yourself! Listen to find out more! ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never…

Shyam is pushed out of his realm of familiarity, when dealing with a clinical station focusing on obstetric anaesthesia. Many folks go into this exam with little obstetric exposure beyond books, and whilst you can pass with book knowledge and some common sense, your life will be easier if you can hangout with the on call obstetric anaesthetist for a few days, or tag along with them when on calls on your end are quiet. Listen to find out more! ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to…

Ever wondered how metaraminol really, really works? Me too, turns out we aren't quite there on true intra-neuronal activity, but there is more to know that just 'indirect' Listen to find out more! > https://gasgasgas.uk/episode/metaraminol ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted upon. This information is not a suitable substitute for medical advice. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these…

Shyam handles the effects of ageing of interest to the anaesthetist, neuroprotective ventilation strategies, endotracheal tubes and laser safety! Listen to find out more! ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted upon. This information is not a suitable substitute for medical advice. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed.…

Core Pharma fun returns with the first foray into the Adrenergics & Friends Chapter with Ephedrine! We naturally cover all the critical curriculum examinable information, and then explore the history of this molecule through the ages (not currently in the curriculum) Listen to find out more! > https://gasgasgas.uk/episode/ephedrine/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted upon. This information is not a suitable substitute for medical advice. Whilst the body of medical…

Shyam handles the autonomic nervous system, GPCRS but does get caught out with regards to receptor down regulation on exposure(beta arrestin pathway) β−Arrestins: Structure, Function, Physiology, and Pharmacological Perspectives Listen to find out more! ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted upon. This information is not a suitable substitute for medical advice. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and…

Shyam first of his name, possible King of the Andals puts his claymore aside and handles the first of four 15 min vivas for the FRCA primary exam! This episode handles core pharmacology to start with dabbles in the milk of the poppy (compare and contrast those opioids) and then TCI models as a nice little closer! Listen to find out more! ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted upon. This information is not a suitable substitute for medical advice. Whilst the body of medical…

The fourth and final Martin from Sweden vivacast episode, he has been prepping for the EDAIC oral exams. This session tackled vapourisers and their safety features, and it identified a gap in Martins knowledge, whether or not the EDAIC would ask such things, is naturally another question, but nevertheless this is important knowhow for the apocalypse (when you are getting the boyles bottle out of the cupboard) Listen to find out more! ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted…

The third of a new panel of vivacast episodes, Martin, all the way from Sweden, who is prepping for the EDAIC oral exams. This session handles some thinking behind liberating the appendix from a 12 year old boy, a structured approach to high airway pressures and managing bronchospasm Listen to find out more! ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted upon. This information is not a suitable substitute for medical advice. Whilst the body of medical knowledge is slowly shifting…

The second of a new panel of vivacast episodes, introducing Martin, all the way from Sweden, who is prepping for the EDAIC oral exams. This session explores the physiological changes of pregnancy, peri partum emergencies and introduces cardiac risk stratification. Listen to find out more! Show notes at: ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted upon. This information is not a suitable substitute for medical advice. Whilst the body of medical knowledge is slowly shifting and…

The First of a new panel of vivacast episodes, introducing Martin, all the way from Sweden, who is prepping for the EDAIC oral exams. This session explores heparin and what happens with a single dose of propfol! Listen to find out more! Show notes at: ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted upon. This information is not a suitable substitute for medical advice. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and…

Anti-Cholinesterases, they find widespread use in clinical medicine. Their role in reversal of neuromuscular blockade is certainly dwindling given sugammadexes rise to post patent [can actually afford to use it] supremacy. But if you are using atracurium, then go nuts! Listen to find out more! Show notes at : https://gasgasgas.uk/anticholinesterases/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted upon. This information is not a suitable substitute for medical advice. Whilst the…

Sugammadex, if Carlsberg made Sugammadex, it might just be the best drug in the world. I.e. if you were to describe a perfect neuromuscular reversal drug, sugammadex is getting very close! Listen to find out more! Show notes at : https://gasgasgas.uk/sugammadex/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted upon. This information is not a suitable substitute for medical advice. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing…

Pancuronium pandemonium, with a dash of Type 1 and Type 2 Block for good measure. Listen to find out more! Show notes at : https://gasgasgas.uk/pancuronium/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted upon. This information is not a suitable substitute for medical advice. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. Where deemed…

Vecuronium for anaesthetists with a segue into NMJ/MNB monitoring! Listen to find out more! Show notes at : https://gasgasgas.uk/vecuronium/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted upon. This information is not a suitable substitute for medical advice. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for these core concepts, as such, accuracy of the content is not guaranteed. Where deemed sensible by the…

Cisatracurium is one of the ten isomers found in an ampoule of Atracurium! It has been selected out as a useful, potent, predictably degrading drug with a very stable side effect profile! Althought, it might be that, whilst Cisatracurium probably sounded like a great idea at the time... it was perhaps batting for a marketing USP that wasn't quite there.. If we were being particularly clever we could call it the R-cis-R'-cis isomer of Atracurium besilate, it is 3 times as potent as the Atracurium mix in your anaesthetic room fridge Listen to find out more! Show notes at: https://gasgasgas.uk/cisatracurium/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas…

Mivacurium, a drug that is perhaps not found in your cupboard anymore! It does have a number of interesting properties, which does make it a worthy exam question and a useful example of geometric isomerism! Listen to find out more Show notes at:https://gasgasgas.uk/mivacurium ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted upon. This information is not a suitable substitute for medical advice. Whilst the body of medical knowledge is slowly shifting and expanding, there are often…

The ubiquity of oxygen in the curriculum is directly correlated with its importance! One of many episodes that focus on the facets o knowledge needed to understand how oxygen does its thing. Today, when too much oxygen is a bad thing, how it is obtained, transported in hospitals and the negative implications of its use + some history that I know you all deeply desire! Show notes at: https://gasgasgas.uk/oxygen-for-the-frca-primary/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted…

Nitrous Oxide, once a corner stone of 'passing the gas' has been progressively displaced by better agents, think sevoflurane with less PONV, remifentanil for rapid titratable pain relief and even desflurane for its speedier offset. This episode handles everything you need to know and more for the exams! Show notes at: https://gasgasgas.uk/ether_enflurane_explosions/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted upon. This information is not a suitable substitute for medical…

The 2025 Bumper Christmas Special, delving into the delights of Ether, Enflurane and Explosions (+ fires, flames and/or power metal) We find out a little bit about the first Ether anaesthetic, and then get to grips with what an explosion is, and why understandably, it was problematic for anaesthetists. Show notes at: https://gasgasgas.uk/ether_enflurane_explosions/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted upon. This information is not a suitable substitute for medical advice.…

I've checked the house, there are no polar bears so we should be fine to talk about this drug. Desflurane is pricey, polar bear poison that you may get examined on! Check it out! Show notes at: https://gasgasgas.uk/desflurane-and-vapourisers/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted upon. This information is not a suitable substitute for medical advice. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and notions for…

With the advent of halothane, smoking, static and other sizzling was back in style! Gone were the explosive diethyl ether, acetylene, trichloroethylene and cyclopropane anaesthetics of the 1950's and with it a new era of fewer explosions, and possibly a greater prevalence of post operative liver distress. Show notes at: https://gasgasgas.uk/halothane/↗ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted upon. This information is not a suitable substitute for medical advice. Whilst the…

Having a solid understanding of Sevoflurane is, as you might expect, quite important for the FRCA primary and your career. as it is likely the most commonly used volatile anaesthetic agent, at least in the UK. Show notes @ https://gasgasgas.uk/sevoflurane-for-the-frca-primary/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted upon. This information is not a suitable substitute for medical advice. Whilst the body of medical knowledge is slowly shifting and expanding, there are often…

This Primary FRCA podcast episode introduces you to Isoflurane, a ubiquitous and fairly cheap volatile anaesthetic agent that always seems to be left alone while its sevoflurane friend lives the high life, This episode probably won't sway your use, but if you walk into an anaesthetic halfway thru and have no idea what your ET for MAC-1 is, then this is for you! GasGasGas - putting knowledge in your brain! Show notes at: https://gasgasgas.uk/isoflurane/↗ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never…

This Primary FRCA podcast episode introduces you to Volatile anaesthetic agents and the pharmaceutical particulars that make their behaviour through a human very interesting! We cover Blood gas and oil gas partition coefficients, Saturated vapour pressure, critical temperature and boiling points - and touch on pharmacodynamics and the Viva Question 'What is the ideal anaesthetic agent' approach. Show notes at: https://gasgasgas.uk/introduction-to-volatile-anaesthetic-agents/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational…

Yet again, the sound engineer has been sacked........ Apologies that this is a second attempt at an Opioids Quiz, the music cuts went rather wrong - so we've slung the music in the bin! This is a straight up quiz, with gaps so you can think up an answer and then, as you might expect... an Answer! The goal isn't to give you verbatim words to regurgitate but to build up these facts in your mind so then next time you cover it you've foundations to build upon! GasGasGas - putting knowledge in your brain! Show notes at: https://gasgasgas.uk/clonidine/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk…

Clonidine is a drug found in many a cupboard, acting as a useful adjunct for pain, sedation and having utility in smoothing out post op emergence, it has off license use as a adjunct in regional and neuraxial blockade (at least in the literature!) Show notes at: https://gasgasgas.uk/clonidine/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted upon. This information is not a suitable substitute for medical advice. Whilst the body of medical knowledge is slowly shifting and expanding,…

Dexemedetomidine is a drug that it seems we are really only just getting our hands on in the UK, it is an Alpha 2 AGOnist causing sedation, anxiolysis and analgesia. This episode of GasGasGas explores its use, mechanisms side effect profile and kinetics Show notes at: https://gasgasgas.uk/dexmedetomidine/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted upon. This information is not a suitable substitute for medical advice. Whilst the body of medical knowledge is slowly shifting and…

Midazolam represents the cornerstone benzodiazepine in perioperative medicine, offering rapid onset sedation, anxiolysis, and amnesia with predictable pharmacokinetics. Understanding its mechanism, dosing strategies, and clinical applications is fundamental for safe anaesthetic practice and optimal patient care. Show notes @: https://gasgasgas.uk/midazolam/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted upon. This information is not a suitable substitute for medical advice. Whilst…

Having an Iota of a Scooby-Doo about Etomidate is perhaps what is required for the FRCA primary exams. We've gone into naturally more detail when we're talking Etomidate for gasgasgas, because we love a bit of detail. This episode covers the pharmacodynamics and pharmacokinetics of Etomidate, but also explores briefly steroidogenesis and what the implications of this is clinically. GasGasGas - putting knowledge in your brain! Show note: https://gasgasgas.uk/etomidate-for-the-frca/ Link you must read since this episode! https://www.thebottomline.org.uk/summaries/icm/rsi-ketamine-or-etomidate-for-tracheal-intubation-of-critically-ill-adults/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA…

Understanding molecular stereochemistry is fundamental to modern anaesthetic practice. The three-dimensional arrangement of atoms within drug molecules directly impacts their pharmacological properties, with some arrangements being therapeutically beneficial while others may be inactive or even harmful. This episode explores the concept of isomerism in anaesthetic drugs, with particular focus on how molecular handedness affects drug choice. Show notes at: https://gasgasgas.uk/classifying-isomers/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All…

Welcome to the final local anaesthetic episode - Peri-neural adjuncts- because we should not forget the medley of mixing options that you could stir into your NRfit cauldron.... although most folks don't. Ketamine, in it goes, give it a stir - a dash of clonidine for a bit of dozy chill - 3 grains of morphia and don't forget the sodium bicarbonate. Show notes at: https://gasgasgas.uk/peri-neural-adjuncts-to-local-anaesthetics/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted upon.…

Welcome to an experimental episode of GasGasGas - where you get the joys of a quiz after listening to all these episodes on local anaesthetics agents. Let me know if you think it's dry as hell. Show notes at: https://gasgasgas.uk/local-anaesthetic-quiz/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted upon. This information is not a suitable substitute for medical advice. Whilst the body of medical knowledge is slowly shifting and expanding, there are often differing numerics and…

Welcome to another essential episode of Gas Gas Gas, where we summarise all the local anaesthetic content we have covered - In order to get you fired up for the most exciting quiz on local anaesthetics you've ever had the pleasure of listening to. Show notes at: https://gasgasgas.uk/comparing-local-anaesthetics/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted upon. This information is not a suitable substitute for medical advice. Whilst the body of medical knowledge is slowly…

Welcome to Local Anaesthetic Systemic Toxicity (LAST) is one of the most significant complications in regional anaesthesia practice. This episode explores the pathophysiology, recognition, and management of LAST with particular emphasis on emergency management protocols and risk mitigation strategies. Understanding LAST is crucial for safe regional anaesthesia practice (in Anaesthetic rooms, surgical fields and for emergency department blocks), as it can occur with any local anaesthetic administration and requires immediate, systematic intervention. ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk…

Today we're exploring ropivacaine - the local anaesthetic you might not see every day, but absolutely need to understand when bupivacaine is in short supply or when examiners want to test your knowledge of enantiomeric purity and differential motor blockade.... Show notes at: https://gasgasgas.uk/ropivacaine/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted upon. This information is not a suitable substitute for medical advice. Whilst the body of medical knowledge is slowly shifting…

Welcome to lidocaine - the ubiquitous local anaesthetic that's everywhere in clinical practice but comes with some important caveats. Whether you're preparing for your primary FRCA exams or just starting your anaesthesia rotations, understanding lidocaine's extensive clinical applications, antiarrhythmic properties, and the growing role of IV infusions for pain management is core know how!. Show notes at: https://gasgasgas.uk/lidocaine/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be…

Welcome to the Prilocaine episode - the local anaesthetic that's often overshadowed by Bupivacaine but deserves a place in your clinical toolkit. Whether you're preparing for your primary FRCA exams or just starting your anaesthesia rotations, understanding Prilocaine's unique properties will help you tailor anaesthesia to patient and surgery, bupivacaine isn't always the answer Show notes at: https://gasgasgas.uk/prilocaine-for-the-frca-primary/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended…

If you like a story about tenacious testicular traction and slamming shins then this is the episode for you. This FRCA Primary Podcast episode explores cocaine and the exposure patients have to it in the clinical environment, chiefly courtesy of the ENT surgeons. The episode explores mechanism, side effects, onset, implications, but also the history of spinal anaesthesia and treatment of cocaine toxicity in the A&E department. Show notes at:https://gasgasgas.uk/cocaine-for-the-frca-primary/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content…

This FRCA Primary Podcast episode burrows into bupivacaine, exploring its friends (additives), mechanism of action, and clinical applications. We'll cover the key differences between neuronal and cardiac action potentials, and discuss why levobupivacaine has become the preferred choice in many clinical scenarios. Show notes at: https://gasgasgas.uk/primary-frca-podcast-episode-31-bupivacaine-and-friends/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted upon. This information is not a…

This FRCA Primary Podcast episode establishes the scientific foundation for understanding how Local Anaesthetic drugs work, why they behave differently and how to use them safely. By the end, you'll understand nerve physiology, sodium channel blockade, drug classification, and the basics of local anaesthetic toxicity. Show notes at: https://gasgasgas.uk/local-anaesthetic-fundamentals-for-the-frca/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted upon. This information is not a…

Opioids are a significant cornerstone of anaesthetic practice, forming part of the triad of anaesthesia with their analgesic properties. We utilise these analgesic properties not just because "surgery hurts," but also because our interventions cause physiological upset - laryngoscopy being a prime example. Show notes at: https://gasgasgas.uk/comparing-opioids-for-the-frca-primary/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted upon. This information is not a suitable substitute for…

Remifentanil is an anaesthetist’s dream: ultra-short acting, reliably titratable, and deeply potent. This episode takes a dual-pronged approach, covering both the FRCA-relevant pharmacology of remifentanil and introducing the Minto target-controlled infusion (TCI) model. Show notes at: https://gasgasgas.uk/remifentanil-and-minto-tci-model/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted upon. This information is not a suitable substitute for medical advice. Whilst the body of…

In this explainer episode of GasGasGas, we make our descent into the joyful complexities of neuraxial opiate pharmacology. Why do we bother putting opiates into this space at all? What governs their journey, how do they behave once administered, and what clinical pearls can be drawn from their behaviour? This episode follows the journey of a single opioid molecule through the fatty labyrinth of the epidural space, across barriers, and into its final destination: the dorsal horn of the spinal cord, before it potters away to realms of mischief in the brainstem. Show notes at: https://gasgasgas.uk/neuraxial-opiate-kinetics-for-the-frca-primary/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA…

In this episode of Gas, Gas, Gas, we drill a figurative oil well into the pharmacology of diamorphine — also known by its more notorious street name, Heroin/Smack/Golden Brown. Diamorphine is a synthetic diacetylated derivative of morphine, and this episode details its mechanism of action, clinical applications, pharmacokinetics, pharmacodynamics, and side effect profile. The episode is structured to support FRCA Primary revision with an irrelevant clinical anecdote (but sound advice I would argue) and exam-focus. Show notes at: https://gasgasgas.uk/diamorphine-for-the-frca-primary/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website:…

We are plunging into the pharmacology of oxycodone, a potent semi-synthetic opioid analgesic widely used in perioperative and chronic pain settings. We explore oxycodone's mechanism of action, pharmacokinetics, and pharmacodynamics We dissect its action on mu-opioid receptors, compare it to morphine and other opioids, and review evidence regarding oral vs intravenous formulations, metabolism via CYP450 enzymes + implications for renal and hepatic impairment. It's lost is license for prolonged release versions in acute pain! Show notes at: https://gasgasgas.uk/oxycodone-for-the-frca-primary/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website:…

In this episode of Gas, Gas, Gas, we drill a figurative oil well into the pharmacology of diamorphine — also known by its more notorious street name, Heroin/Smack/Golden Brown. Diamorphine is a synthetic diacetylated derivative of morphine, and this episode details its mechanism of action, clinical applications, pharmacokinetics, pharmacodynamics, and side effect profile. The episode is structured to support FRCA Primary revision with an irrelevant clinical anecdote (but sound advice I would argue) and exam-focus. Show notes at: https://gasgasgas.uk/diamorphine-for-the-frca-primary/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website:…

This episode takes a dive into the detailed pharmacology of Tramadol focussing on the content for the FRCA Primary exam. We explore its unique multi-mechanism analgesic action, pharmacokinetics, clinical uses, and key points. Show notes at: https://gasgasgas.uk/tramadol-for-frca-primary-exam/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted upon. This information is not a suitable substitute for medical advice. Whilst the body of medical knowledge is slowly shifting and expanding,…

In this episode of GasGasGas, we explore Alfentanil, a short-acting μ-opioid receptor agonist pivotal for anaesthetic practice. Discovered in 1976 by Janssen Pharmaceuticals, Alfentanil remains a super handy agent, especially for (modified) rapid-sequence inductions and acute pain management. Show notes at https://gasgasgas.uk/alfentanil-for-the-frca-primary/ ================================================ GasGasGas - Covering Anaesthetic Science for Anaesthetists! Sponsored by Teach Me Anaesthetics Check out the Teach Me Anaesthetics 1100+ SBA Resource (affiliate link) ================================================ Dr Gas Lurks On: BlueSky: Gas Gas Gas (@gasgasgaspodcast.bsky.social) X / Twitter: GasGasGasFRCA (@GasGasGasFRCA) / X Facebook: Facebook - Gas Gas Gas Website: www.gasgasgas.uk ================================================ Disclaimer / Sage Advice All content is educational in nature and never intended to be acted upon. This information is not a suitable substitute for medical advice.…